Because of Powtoon's similarity to Creative Commons, I think a great way to integrate it into classroom instruction would be to create instructional videos with it. It lends itself very nicely to presenting information and statistics as well. It could also be used successfully in digital storytelling.
For teachers of older students, Powtoon has a really unique resume example. I could see having students create a digital resume in addition to a traditional example.
Don't take my word for it, go to to Powtoon and request an invitation!